Sodium floods in (phase 0: depolarization). Then, open, repolarizing you (phase 3). But a special class of calcium-dependent potassium channels ensures you have an afterhyperpolarization — a refractory period so you don't fire chaotically.
One day, you receive an urgent message from the . A structure called the subthalamic nucleus has fired a burst of glutamate (excitatory) at your rival, an inhibitory neuron in the globus pallidus internus (GPi) . That GPi neuron normally clamps down on the thalamus like a hand squeezing a hose. But now, GPi is silenced. brain bee study guide
At the NMJ, the enzyme — sitting on the basal lamina — rapidly cleaves ACh into acetate and choline. Choline is taken back up into the LMN via the choline transporter (CHT1) , then reused. Sodium floods in (phase 0: depolarization)